Minimally invasive procedures are becoming the go-to solution for patients seeking natural, effective skin improvements. But for practitioners, deciding between microneedling, PRP or mesotherapy is not always obvious. Each technique stimulates the skin differently, involves different mechanisms, and suits different clinical scenarios. Understanding how they work — and when to use them — is key to tailoring effective protocols.
Microneedling: small punctures, visible renewal
Microneedling uses tiny sterile needles to create microchannels in the epidermis. These controlled injuries stimulate the body’s natural healing response — increasing collagen, elastin, and cell turnover.
When does it work best?
Microneedling is a solid choice for fine lines, acne scars, uneven texture and enlarged pores. It enhances skin density and tone over time. On its own, however, it may lack hydrating power. That’s why many protocols combine it with serums containing hyaluronic acid, peptides or antioxidants — helping the skin both rebuild and recharge.
This synergy between physical stimulation and active ingredients can significantly boost the end result. The goal isn't only micro-injury; it's also micro-infusion.
PRP: regenerating with your own biology
Platelet-Rich Plasma (PRP) involves drawing the patient’s blood, centrifuging it, and re-injecting the plasma fraction rich in growth factors. It’s a pure form of biostimulation — no synthetic ingredients, just your body’s own regenerative messengers.
What can PRP help with?
Skin laxity, thinning hair, tear trough hollowing or fine crepe-like wrinkles respond well to PRP. It promotes collagen production, improves vascularization, and supports tissue repair.
It’s a technique that requires precision and proper equipment (like RegenLab® kits) to ensure safety and efficacy. While results aren’t immediate, they unfold gradually over several weeks. The effects are subtle but deeply regenerative.
Mesotherapy: microdosing with active ingredients
Mesotherapy uses microinjections to deliver a customized blend of hyaluronic acid, vitamins, amino acids and antioxidants directly into the superficial dermis. The goal isn’t to fill — but to nourish, hydrate and stimulate from within.
Who benefits from mesotherapy?
Patients with dull, dehydrated, tired or mature skin often see visible improvements in tone, elasticity and hydration. It’s an ideal option for early signs of aging and prevention strategies.
With targeted products like Pluryal® Mesoline, you can adapt your protocol to the patient's specific concerns — skin brightness, firmness, or even scalp revitalization.
Does it require multiple sessions?
Yes. Mesotherapy is cumulative by nature. Results improve with repeated applications, typically spaced every few weeks. Over time, it helps recondition the skin and maintain its resilience.
Three methods, three pathways
Microneedling works by mechanical stimulation. PRP activates biological repair using the body’s own tools. Mesotherapy delivers concentrated, bioavailable ingredients to restore hydration and tone.
They don’t compete — they complement. Practitioners frequently combine them. Think of microneedling followed by PRP, or alternating PRP and mesotherapy depending on the area. Personalization is the logic behind today’s skin treatments.
What about tolerance?
All three techniques are generally well-tolerated. Mild redness, swelling or bruising may occur — temporary and usually minimal. Product quality, proper technique and clinical experience remain central to safety and patient satisfaction. The solutions distributed by Vivacy Canada meet strict quality standards, with proven clinical efficacy and skin compatibility.
More than a technique — it’s a treatment vision
There is no universal protocol. A successful cosmetic treatment begins with a skin diagnosis, a structured plan, and a clear understanding of how each method supports the skin’s biology.
Skin needs hydration, stimulation, and repair — in different ways, at different times. Whether you use microneedling to restructure, PRP to rejuvenate, or mesotherapy to deeply hydrate, your choice should align with the skin’s actual condition and goals.
